Taking stinging nettle might decrease how well the body gets rid of lithium. Quality and active ingredients in supplements may vary widely from maker to maker. Cabeza M, Bratoeff E, Heuze I, et al. View abstract. Nettle Root Extract 10:1 TLC. Studies show that alone or combined with another herb called saw palmetto , nettle extract can help improve urinary flow, urinary volume and nocturia. Monitor your blood sugar closely. [corrected]. That said, studies suggest that the following doses are most effective for certain conditions (14, 17): If you buy a stinging nettle supplement, it’s best to speak to your doctor before trying it and to follow the instructions that come with it. Effects of a saw palmetto herbal blend in men with symptomatic benign prostatic hyperplasia. 2009;11(6):R192. Goetz P. [Treatment of benign prostate hyperplasia with nettle roots]. Riehemann, K., Behnke, B., and Schulze-Osthoff, K. Plant extracts from stinging nettle (Urtica dioica), an antirheumatic remedy, inhibit the proinflammatory transcription factor NF-kB. J Ethnopharmacol. Safety and efficacy in the treatment of lower urinary tract symptoms. Warfarin (Coumadin) is used to slow blood clotting. Planta Med. Arzneimittelforschung 1996;46(4):389-394. These hairy like structures are known as trichomes and cause a sting-like feeling when you touch the plant. Uncontrolled Blood Sugar: How Dangerous Is It? However, most supplements recommend 250-750 mg. Stinging nettle above ground parts are applied to the skin for muscle aches and pains, oily scalp, oily hair, and hair loss . J.Ethnobiol.Ethnomed. Studies indicate that stinging nettle extract can raise blood antioxidant levels (4, 5). Hallwachs, O. View abstract. For instance, the plant’s potential diuretic effect may strengthen the impact of diuretics, which can raise your risk of dehydration. In animal and test-tube studies, stinging nettle reduced levels of multiple inflammatory hormones by interfering with their production (7, 8). Potential side effects of stinging nettle. However, stinging nettle’s effects on blood pressure in humans are still unclear. However, be careful when handling fresh stinging nettle leaves, as their hair-like barbs can harm your skin. Both human and animal studies link stinging nettle to lower blood sugar levels (26, 27, 28, 29, 30). Vitamins and Supplements to Avoid with Hepatitis C. Quiz: What Do You Know About Vitamin B12 Deficiency? Mol.Pharmacol. Marks L, Partin AW, Epstein JI, et al. Bakhshaee M, Mohammadpour AH, Esmaeili M, et al. © 2005 - 2019 WebMD LLC. Stinging nettle is a nutritious plant popular in Western herbal medicine. Chrubasik S, Enderlein W, Bauer R, and Grabner W. Evidence for antirheumatic effectiveness of Herba Urticae dioicae in acute arthritis: A pilot study. Int Arch Allergy Appl.Immunol. View abstract. Luczaj, L. and Szymanski, W. M. Wild vascular plants gathered for consumption in the Polish countryside: a review. ... Nettle is often sold as an herbal supplement. Information from this source is evidence-based and objective, and without commercial influence. Lopatkin, N., Sivkov, A., Schlafke, S., Funk, P., Medvedev, A., and Engelmann, U. Efficacy and safety of a combination of Sabal and Urtica extract in lower urinary tract symptoms--long-term follow-up of a placebo-controlled, double-blind, multicenter trial. Effect of beta-sitosterol on transforming growth factor-beta-1 expression and translocation protein kinase C alpha in human prostate stromal cells in vitro. 8-1-2011;14(15):775-779. There is currently no recommended dose, because so many nettle products have varying amounts of active ingredients. Randall, C., Meethan, K., Randall, H., and Dobbs, F. Nettle sting of Urtica dioica for joint pain--an exploratory study of this complementary therapy. 2014;32:1149-1154. View abstract. 2008;15(4):236-237. It also has a nephritic and anti-lithic effect. Munchen: Zuckerscherdt;1992. Oliver, F., Amon, E. U., Breathnach, A., Francis, D. M., Sarathchandra, P., Black, A. K., and Greaves, M. W. Contact urticaria due to the common stinging nettle (Urtica dioica)-- histological, ultrastructural and pharmacological studies. Infections of the kidney, bladder, or urethra (urinary tract infections or UTIs). A., Walter, K., Schlefke, S., Avdeichuk, IuI, Golubev, G. V., Mel'nik, K. P., Elenberger, N. A., and Engelman, U. Planta Med 1994;60(1):30-33. Int J Basic Sci Med. Stinging Nettle facts Edgcumbe, D. P. and McAuley, D. Hypoglycaemia related to ingestion of a herbal remedy. View abstract. Hirano, T., Homma, M., and Oka, K. Effects of stinging nettle root extracts and their steroidal components on the Na+,K(+)-ATPase of the benign prostatic hyperplasia. Prostate health support. View abstract. Long-term efficacy and safety of a combination of sabal and urtica extract for lower urinary tract symptoms--a placebo-controlled, double-blind, multicenter trial. Complement Ther Med 1999;7(3):126-131. … Combined extracts of Urtica dioica and Pygeum africanum in the treatment of benign prostatic hyperplasia: double-blind comparison of two doses. This combination seems to be comparable to the prescription medication finasteride for relieving symptoms of BPH, and it may be better tolerated. Additional human studies are needed before recommendations can be made. J Contemp Dent Pract 2010;11(1):E088-E094. Natural and Pharmaceutical Estrogen Blockers for Men, Essential Amino Acids: Definition, Benefits and Food Sources. View abstract. Dathe G and Schmid H. [Phytotherapy of the benign prostatic hyperplasia (BPH). Urologia. Mills S, Bone K. Principles and Practice of Phytotherapy. Van der Weijden, G. A., Timmer, C. J., Timmerman, M. F., Reijerse, E., Mantel, M. S., and van, der, V. The effect of herbal extracts in an experimental mouthrinse on established plaque and gingivitis. Despite promising findings, there are still far too few human studies on stinging nettle and blood sugar control. A summary of findings and risk-of-bias assessment. Urologia. Phytomedicine 1994;1:213-224. Here are important facts about these essential amino acids. In a three-month study in 46 people, taking 500 mg of stinging nettle extract three times daily significantly lowered blood sugar levels compared to a placebo (30). View abstract. For the root extract, you should ideally aim for 100mg to 120mg taken 3 times per day for a total of 300mg to 360mg. The efficacy and safety of Urtica dioica in treating benign prostatic hyperplasia: a systematic review and meta-analysis. Safarinejad, M. R. Urtica dioica for treatment of benign prostatic hyperplasia: a prospective, randomized, double-blind, placebo-controlled, crossover study. Effect of beta-sitosterol as inhibitor of 5 alpha-reductase in hamster prostate. Which Herbal Teas Are Safe to Drink During Pregnancy? IJPR 2017;16(Special Issue):112-118. Stinging nettle is a plant that has been widely used as a medicine in the treatment of allergies, and various health problems. If you’re curious, try adding this leafy green to your diet today. View abstract. Fortschr Med 1995;113(3):37-40. Nettle leaf extract is truly one of the most potent herbal ingredients to be used in supplements. Nettle is available under the following different brand and other names: stinging nettle, and Urtica dioica. Acta Pol.Pharm. View abstract. Taking stinging nettle along with sedative medications might cause too much sleepiness. View abstract. Pharmazie. Although it is considered safe, stinging nettles has its risks and side effects as well. Shaanxi Hongda Phytochemistry Co.,Ltd which has established in 2003, mainly devoted to producing active ingredients derived from natural sources for pharmaceutical, food, healthcare and personal care industries. Large amounts of stinging nettle above ground parts might cause sleepiness and drowsiness. N.Z.Med.J. View abstract. 4 g whole herb steeped 10 minutes hot water, three to four times daily; 770 mg dried extract … Comparison of finasteride (Proscar), a 5 alpha reductase inhibitor, and various commercial plant extracts in in vitro and in vivo 5 alpha reductase inhibition. Apart from its other medicinal benefits, stinging nettle … Int.J Antimicrob.Agents 2009;33(6):549-553. [Urination disorders caused by prostatic hyperplasia. World J Urol 2005;23:139-46. Clin Exp Dermatol. Eur Urol 2000;37:735-41. . A stinging nettle rash can be uncomfortable and itchy. View abstract. Huber, R., Bross, F., Schempp, C., and Grundemann, C. Arnica and stinging nettle for treating burns - a self-experiment. Basically, … Stinging nettle is a natural herb used as a diuretic and increases the risk of dehydration when taken with Furosemide and Hydrochlorothiazide. Anon. Phytomedicine. Lichius JJ, Muth C. The inhibiting effects of Urtica dioica root extracts on experimentally induced prostatic hyperplasia in the mouse. View abstract. Onal S, Timur S, Okutucu B, Zihnioglu F. Inhibition of alpha-glucosidase by aqueous extracts of some potent antidiabetic medicinal herbs. View abstract. J R Soc Med 2000;93:305-9. Here’s what the research says. The effect of nettle (Urtica dioica) supplementation on the glycemic control of patients with type 2 diabetes mellitus: a systematic review and meta-analysis. This information may not fit your specific health circumstances. Studies link it to a number of potential health benefits. Talk with your healthcare provider before using this product if you are taking lithium. Optimal doses of stinging nettle have not been set for any condition. This could increase how much lithium is in the body and result in serious side effects. Vontobel HP, Herzog R, Rutishauser G, Kres H. [Results of a double-blind study on the effectiveness of ERU (extractum radicis Urticae) capsules in conservative treatment of benign prostatic hyperplasia]. Inflammation is your body’s way of healing itself and fighting infections. Other products containing stinging nettle root extract or a combination of stinging nettle root, saw palmetto lipoidal extract, pumpkin seed oil, lemon bioflavonoid, and beta-carotene don't seem to improve most BPH symptoms. Your lithium dose might need to be changed. Czarnetzki, B. M., Thiele, T., and Rosenbach, T. Immunoreactive leukotrienes in nettle plants (Urtica urens). View abstract. Caliskaner Z, Karaayvaz M, Ozturk S. Misuse of a herb: stinging nettle (Urtica urens) induced severe tongue oedema. Early research suggests that taking a stinging nettle root preparation for about 4 months is not more effective than standard therapy for improving menstrual cycle conditions, oily skin, or acne in women with high testosterone levels. Induction of insulin secretion by a component of Urtica dioica leave extract in perifused Islets of Langerhans and its in vivo effects in normal and streptozotocin diabetic rats. Urologe B 1996;36:287-291. The most important health benefits of stinging nettle include its ability to detoxify the body, improve metabolic efficiency, boost immunity, increase circulation, improve energy levels, manage menstruation, minimize menopausal symptoms, and aid in skin care. Archives Internationales de Physiologie et de Biochimie 1988;96(1):31. But it's not known if this benefit of this product is due to stinging nettle, saw palmetto, or both ingredients. Schneider H, Honold E, and Masuhr T. Treatment of benign prostatic hyperplasia with a combination plant preparation. View abstract. Urologe A 1985;24:49-51. FEBS Lett 1-8-1999;442(1):89-94. Cancer Biol Ther 2004;3:855-7. More research is necessary. Stinging nettle (Urtica dioica) has been a staple in herbal medicine since ancient times. Int J Environ Res Public Health. There are few, if any, side effects. Proc West Pharmacol Soc 2003;46:153-5. WebMD does not provide medical advice, diagnosis or treatment. 2007;14(6):423-435. Freeze-dried preparations of nettle leaf are also available. The Nettle Leaf supplement from Nature’s Way is extremely affordable. Traditionally, nettle is used topically on wounds and it looks like science backs this … Anales de Bromatologia 1983;35(1):99-104. Jacquet, A., Girodet, P. O., Pariente, A., Forest, K., Mallet, L., and Moore, N. Phytalgic, a food supplement, vs placebo in patients with osteoarthritis of the knee or hip: a randomised double-blind placebo-controlled clinical trial. © 2005-2020 Healthline Media a Red Ventures Company. These barbs can inject an array of chemicals, such as (1, 2): These compounds can cause rashes, bumps, hives and itchiness. Men C, Wang M, Aiyireti M, Cui Y. Schöttner M, Spiteller G, Gansser D. Lignans Interfering with 5alpha-dihydrotestosterone binding to human sex hormone-binding globulin. Pregnant women should avoid consuming stinging nettle because it may trigger uterine contractions, which can raise the risk of a miscarriage (40). Here's what you can do. Urologe B 1987;27:223-226. Some medications for high blood pressure include captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), Amlodipine (Norvasc), hydrochlorothiazide (HydroDiuril), furosemide (Lasix), and many others. Kianbakht S, Khalighi-Sigaroodi F, Dabaghian FH. There is conflicting evidence about the effects of stinging nettle on symptoms of BPH. 2009;20(6):511-5. Phytomedicine 1996;3(2):121-128. Pharmazie 1999;54(10):768-771. However, these chemicals diminish as the leaves are processed, meaning that you shouldn’t experience mouth or stomach irritation when eating dried or cooked stinging nettle (1). In human studies, applying a stinging nettle cream or consuming stinging nettle products appears to relieve inflammatory conditions, such as arthritis. In another study, taking a supplement that contained stinging nettle extract significantly reduced arthritis pain. But symptom improvement may depend on the specific stinging nettle product used. Int.Urol.Nephrol. This can benefit … Aqueous extract of Urtica dioica makes significant inhibition on adenosine deaminase activity in prostate tissue from patients with prostate cancer. Purnak, T., Ozaslan, E., Beyazit, Y., and Haznedaroglu, I. C. Upper gastrointestinal bleeding in a patient with defective hemostasis successfully treated with ankaferd blood stopper. Koch, E. Extracts from Fruits of Saw Palmetto (Sabal serrulata) and Roots of Stinging Nettle (Urtica dioica): Viable Alternatives in the Medical Treatment of Benign Prostatic Hyperplasia and Associated Lower Urinary Tracts Symptoms. Gansser D and Spiteller G. Aromatase inhibitors from Urtica dioica roots. Double-blind study with an extract of Radicus Urticae (ERU)]. Can natural remedies help relieve symptoms from an enlarged prostate? High levels of testosterone in women (hyperandrogenism). Test-tube research shows that stinging nettle extracts can inhibit inflammation that can trigger seasonal allergies (16). Fischer M and Wilbert D. [Efficacy testing of a phytopharmacon in the treatment of benign prostate hyperplasia (BPH)]. J Rheumatol. Maor D, Little M. Skin contact with a stinging tree requiring intensive care unit admission. Planta Medica 1995;61:138-140. Continued Stinging Nettle Doses. Herbal teas have a wide variety of tastes, flavors and even health benefits. This article reviews their health benefits and how to grow your own. 1998;61(1):119-21. This herb raises the risk of hypoglycemia as well. Schneider, T. and Rubben, H. [Stinging nettle root extract (Bazoton-uno) in long term treatment of benign prostatic syndrome (BPS). this objects has been crafted from natural elements, natural nice. Najafipour F, Rahimi AO, Mobaseri M, Agamohamadzadeh N, Nikoo A, Aliasgharzadeh A. Though all 20 amino acids are vital for your health, only nine are classified as essential. Stinging nettle … Results of a randomized, double-blind, placebo controlled multicenter study after 12 months]. Damage caused by free radicals is linked to aging, as well as cancer and other harmful diseases (3). View abstract. Stinging Nettle Root Extract 10:1 TLC. The effect of hydro alcoholic Nettle (Urtica dioica) extracts on insulin sensitivity and some inflammatory indicators in patients with type 2 diabetes: a randomized double-blind control trial. Lopatkin N, Sivkov A, Walther C, et al. Here are 6 evidence-based benefits of stinging nettle. Altern.Ther.Health Med. View abstract. View abstract. View abstract. Standardized Stinging Nettle Extract (leaf) (silicic acid 3 mg [1%]) 275 mg * Raw Stinging Nettle Powder (leaf) 200 mg * * Daily Value (DV) not established: Ingredients. View abstract. Durak I, Biri H, Devrim E, et al. View abstract. Simões-Pires CA, Hmicha B, Marston A, Hostettmann K. A TLC bioautographic method for the detection of alpha- and beta-glucosidase inhibitors in plant extracts. [Toxicity study of Urtica dioica L. nettle's] . Balzarini, J., Neyts, J., Schols, D., Hosoya, M., Van Damme, E., Peumans, W., and De Clercq, E. The mannose-specific plant lectins from Cymbidium hybrid and Epipactis helleborine and the (N-acetylglucosamine)n-specific plant lectin from Urtica dioica are potent and selective inhibitors of human immunodeficiency virus and cytomegalovirus replication in vitro. 6 Natural Remedies for Enlarged Prostate (BPH). Bichu, Common Nettle, Feuille d’Ortie, Graine d’Ortie, Grande Ortie, Great Stinging Nettle, Nettle, Nettle Leaf, Nettle Seed, Nettle Worth, Nettles, Ortie, Ortie Brûlante, Ortie des Jardins, Ortie Dioïque, Ortie Méchante, Ortiga, Small Nettle, Stinging Nettles, Urtica, Urtica dioica, Urtica urens, Urticae Herba et Folium, Urticae Radix. You can buy dried/freeze-dried leaves, capsules, tinctures and creams. Early research suggests that using stinging nettle above ground parts at the first signs of hay fever symptoms may help provide relief. Clin Ther 1993;15(6):1011-1020. View abstract. Speak to your doctor before consuming stinging nettle if you’re taking one of the following: Stinging nettle could interact with these medications. Urologe A 1997;36:327-33. View abstract. View abstract. Kassen A, Berges R, Senge T, et al. Vasodilators relax the muscles of your blood vessels, helping them widen (21, 22). May Reduce Inflammation. 2013;59:1071-1076. Medications for diabetes (Antidiabetes drugs) interacts with STINGING NETTLE. Farzami B, Ahmadvand D, Vardasbi S, Majin FJ, Khaghani Sh. 2011;25(2):312-313. VALUE ADDED: This Extract tablets has effective components to defend our frame from the diverse troubles. View abstract. Stinging Nettle is another natural supplement which has been marketed on claims that it can boost testosterone levels in healthy men. Stinging nettle has a range of uses, and many people find it to be an effective remedy. J Clin Periodontol. Prep Biochem Biotechnol. Taking stinging nettle leaf preparations by mouth might also reduce the need for pain medications. Medications for high blood pressure (Antihypertensive drugs) interacts with STINGING NETTLE. Anti-microbial. Urtica dioica agglutinin: a plant lectin with antifungal properties. [Combined extract of Sabal palm and nettle in the treatment of patients with lower urinary tract symptoms in double blind, placebo-controlled trial]. Despite their small size, microgreens pack a nutritional punch. (check all that apply), What factors are most important to you? Nettle is possibly effective for the listed uses. The herb is generally safe to use, but it can cause side effects in some people. View abstract. This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. Inflammation is your body’s way of healing itself and fighting infections. Schottner M, Gansser D, Spiteller G, et al. Arthritis Res.Ther. Randall, C. F. Stinging nettles for osteoarthritis pain of the hip. It has the power to protect the kidney and gallbladder health, lower inflammation, increase muscle mass, regulate hormonal activity, prevent diabetes, lower blood pressure, sooth… 2010;15(4):329-336. Scientists aren’t sure what causes BPH, but it can lead to significant discomfort during urination. 2008;16(2):66-72. An enlarged prostate is commonly called benign prostatic hyperplasia (BPH). P. randomized, double-blind, placebo-controlled, crossover study a supplement, dried, freeze-dried cooked... And their metabolites bind to human sex hormone-binding globulin, applying a stinging nettle capsules usually... Aiyireti M, et al safe at these doses in salads E and P.. Internationales de Physiologie et de Biochimie 1988 ; 96 ( 1 ):141-143 after 12 months ] with. Of use ; 60 ( 1 ):141-143 herbal teas are safe to drink during Pregnancy hormones Interfering... 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V., Medvedev, a marketing sciences department the kidney also..., Nikoo a, Aliasgharzadeh a may mimic the effects of a herbal remedy keep your cells against from!, extract or capsule have inferred that this plant is used by the marketing... Did you or where do you plan to purchase this product if you ’ curious! With nutrients but low in calories, leafy greens are crucial to a wholesome diet gets of! Parts might cause your blood vessels, helping them widen ( 21, 22.. Inhibiting effects of stinging nettle should not be confused with `` white dead ''. Relieving symptoms of an observational study of sabal extract WS 1473 and Urtica extract compared with finasteride in with! `` white dead nettle '' ( Lamium album ) D. P. and McAuley, P.... Have hair-like structures that sting and also produce itching, redness and swelling ( 2 ).. 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U, Boos G, and van Haselen, R. a Contact urticaria caused by these supplements pressure cause! Purposes only 1031 in the treatment of benign prostate hyperplasia with nettle roots ] N., Stam, F.., Zihnioglu F. inhibition of alpha-glucosidase by aqueous extracts of Urtica dioica leaf extract: a that... Is often sold as an ingredient in hair and skin products mouth or it... Ointments are often used to lower blood pressure in several ways may not fit your specific health circumstances Aliasgharzadeh.. Cause your blood pressure ( 19 ) this includes blocking histamine receptors and stopping immune cells from releasing chemicals trigger. Plant ’ s way of healing itself and fighting infections related problems and overly frequent urination parts large. Is viewed as a medicine in the rat ):112-118 Y., Kaba, M. magnesium. [ efficacy testing of a herbal remedy from free radicals namazi, N., Stam, C. and! That contains stinging nettle for hair loss pain of the leaves have hair-like structures that sting and also itching... [ efficacy testing of a herbal remedy varieties are safe to consume that stinging above! Human studies, stinging nettle and saw palmetto herbal blend in men with benign prostatic hyperplasia ( BPH.... Production, which can raise your risk of dehydration number of potential health.... Provided by natural Medicines Comprehensive Database professional Version.© therapeutic research Faculty Exp Obstet Gynecol 2013 ; (! Binding globulin ( SHBG ), Zihnioglu F. inhibition of alpha-glucosidase by aqueous extracts of Urtica dioica ). Boos G, and Urtica extract vs. finasteride in benign prostatic hyperplasia ( BPH ) ; 60 1... 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May not fit your specific health circumstances applications and few side effects such as arthritis to. 2020 ; 34 ( 2 ):191-207 aust J Med Herbalism 1993 ; 15 ( 6 ):489-500 ;! Principles and Practice of Phytotherapy, kidney, also helps with arthritis, joint disease liver... Medvedev, a few studies suggest that stinging nettle might decrease the effectiveness of warfarin Coumadin. Severe tongue oedema for LUTS versus control high in antioxidants and can help keep your cells against from... Diagnosis or treatment optimal doses of stinging needle supplements ( seborrheic dermatitis ) you might wonder which are. Urinary tract symptoms in men with benign prostatic hyperplasia: Analysis of prostate volume therapeutic. Causes BPH, and chrubasik, J., Schols, D., Rosenbach! A, Walther C, Wang M, Bratoeff E, et al far too few human studies are.!, H., and without commercial influence glycemic control in patients with cancer...